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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Thyrotropin receptor' and Ligand = 'BDBM50614118'
TargetThyrotropin receptor(Human)
Byondis

Curated by ChEMBL
LigandPNGBDBM50614118(CHEMBL5288635)
Affinity DataIC50:  74nMAssay Description:Antagonist activity at human TSHR expressed in HEK293 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetThyrotropin receptor(Rat)
Byondis

Curated by ChEMBL
LigandPNGBDBM50614118(CHEMBL5288635)
Affinity DataIC50:  234nMAssay Description:Antagonist activity at TSHR in rat FRTL-5 cells assessed as reduction in cAMP production incubated for 2 hrs by Eu-cAMP tracer based TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed