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Found 2 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 4' and Ligand = 'BDBM50177125'
TargetToll-like receptor 4(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177125(6-(2-Chloro-4-fluoro-phenylsulfamoyl)-cyclohex-1-e...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human TLR4-mediated cytokine production in mouse macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177125(6-(2-Chloro-4-fluoro-phenylsulfamoyl)-cyclohex-1-e...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human TLR4 expressed in HEK-Blue cells assessed as decrease in LPS-induced TLR4 response incubated for 1 hr followed by LPS stimulation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed