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Found 2 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 4' and Ligand = 'BDBM50595028'
TargetToll-like receptor 4(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595028(CHEMBL5174883)
Affinity DataIC50:  4.80nMAssay Description:Antagonist activity at human TLR4 expressed in HEK-blue hTLR4/MD2-CE14 cells cotransfected with pISRE-TA plasmid assessed as reduction in ISRE activa...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetToll-like receptor 4(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50595028(CHEMBL5174883)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at human TLR4 expressed in HEK-blue hTLR4/MD2-CE14 cells cotransfected with pNiFty plasmid assessed as reduction in NF-kappaB act...More data for this Ligand-Target Pair
In DepthDetails PubMed