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Found
1
Enz. Inhib. hit(s) with Target = 'Transcriptional enhancer factor TEF-1' and Ligand = 'BDBM574627'
Target
Transcriptional enhancer factor TEF-1
(Homo sapiens)
Ikena Oncology
US Patent
Ligand
BDBM574627
(US11458149, Compound I-334 isomer 1)
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Affinity Data
EC50: <100nM
Assay Description:
TEAD inhibition can be assayed using Hippo Pathway TEAD Reporter—MCF7 Cell Line (BPS Bioscience, Catalog #: 60618).
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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