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Found 2 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM50227083'
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50227083(CHEMBL173443)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human TRPM8 expressed in HEK293T cells assessed as blocked of menthol-activated current by whole cell patch clamp electrophysiology rel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50227083(CHEMBL173443)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human TRPM8 expressed in HEK293 cells assessed as reduction in H2O2-induced intracellular calcium flux after 30 mins by Fluo4-AM dye ba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed