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1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1' and Ligand = 'BDBM120394'
Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals
US Patent
Ligand
BDBM120394
(US8703771, 7)
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Affinity Data
IC50: 411nM
pH: 7.5 T: 2°C
Assay Description:
The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...
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