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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1' and Ligand = 'BDBM332703'
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM332703(US10196378, Compound C06)
Affinity DataKi:  2nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM332703(US10196378, Compound C06)
Affinity DataKi:  2nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM332703(US10196378, Compound C06)
Affinity DataIC50:  637nMAssay Description:Inhibition of NanoLuc-tagged ABL1 wild type (unknown origin) expressed in HEK293 cells by NanoBRET TE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed