Report error Found 5 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1' and Ligand = 'BDBM445949'
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 18.4nMAssay Description:ADP-Glo assay kit was purchased from Promega. Magnesium chloride (MgCl2), bovine serum albumin (BSA), ethylene glycol-bis(β-aminoethyl ether)-N,...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 18.4nMAssay Description:c-abl kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/μl) is incubated w...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 18.4nMAssay Description:ADP-Glo assay kit was purchased from Promega. Magnesium chloride (MgCl2), bovine serum albumin (BSA), ethylene glycol-bis(β-aminoethyl ether)-N,...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 18.4nMAssay Description:c-abl kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/μl) is incubated w...More data for this Ligand-Target Pair