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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1' and Ligand = 'BDBM446064'
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM446064(US10669246, Example 121 | US10968188, Example 121)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM446064(US10669246, Example 121 | US10968188, Example 121)
Affinity DataIC50:  12.7nMAssay Description:ADP-Glo assay kit was purchased from Promega. Magnesium chloride (MgCl2), bovine serum albumin (BSA), ethylene glycol-bis(β-aminoethyl ether)-N,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTyrosine-protein kinase ABL1(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM446064(US10669246, Example 121 | US10968188, Example 121)
Affinity DataIC50:  12.7nMAssay Description:c-abl kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/μl) is incubated w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent