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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM60898'
TargetTyrosine-protein kinase BTK(Human)
Principia Biopharma

US Patent
LigandPNGBDBM60898(US9090621, 83B | US9572811, Example 83A)
Affinity DataIC50:  1.40nMT: 25°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of Formula...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTyrosine-protein kinase BTK(Human)
Principia Biopharma

US Patent
LigandPNGBDBM60898(US9090621, 83B | US9572811, Example 83A)
Affinity DataIC50:  16nMT: 25°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of Formula...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetTyrosine-protein kinase BTK(Human)
Principia Biopharma

US Patent
LigandPNGBDBM60898(US9090621, 83B | US9572811, Example 83A)
Affinity DataIC50:  16nMT: 25°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of Formula...More data for this Ligand-Target Pair
In DepthDetails US Patent