Found 4 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ITK/TSK' and Ligand = 'BDBM50015271'
Affinity DataKi: 0.800nMAssay Description:Inhibition of full-length ITK (unknown origin) using biotin-EQEDEPEGIYGVLF-NH2 as substrate by plate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as reduction in PLC-gamma phosphorylation after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 231nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as decrease in phosphorylation of PLC-gamma1 by immunodetection assayMore data for this Ligand-Target Pair