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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM569298'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM569298(US11427563, Compound 53 | US11427563, Compound 62)
Affinity DataIC50:  6.5nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM569298(US11427563, Compound 53 | US11427563, Compound 62)
Affinity DataIC50:  16nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent