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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1 [850-1154]' and Ligand = 'BDBM458893'
Target
Tyrosine-protein kinase JAK1 [850-1154]
()
Almirall
US Patent
Ligand
BDBM458893
(US10759793, Example 45)
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Affinity Data
IC50: 4nM
Assay Description:
The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...
More data for this Ligand-Target Pair
Target Info
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Ligand Info
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US Patent
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