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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1 [866-1154]' and Ligand = 'BDBM489174'
Target
Tyrosine-protein kinase JAK1 [866-1154]
(Homo sapiens (Human))
Astrazeneca
US Patent
Ligand
BDBM489174
((R)-2-((R)-2,4- dimethylpiperazin-1- yl)-N-(3-(5-f...)
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Affinity Data
IC50: <3nM
Assay Description:
Enzyme inhibition studies were performed using recombinant JAK1 (amino acids 866-1154, Life Technologies, #PV4774, Carlsbad, Calif.), JAK2 (amino aci...
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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