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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50527404'
TargetTyrosine-protein kinase JAK2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50527404(CHEMBL4514898 | US10981911, Example 62)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of JAK2-JH1/JH2 domain (532 to 1132 residues) (unknown origin) pre-incubated before NH2-KGGEEEEYFELVKK-CO2 substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50527404(CHEMBL4514898 | US10981911, Example 62)
Affinity DataIC50:  148nMAssay Description:Inhibition of JAK2/JAK2 in human PBMC assessed as reduction in GM-CSF-induced STAT5 phosphorylation pre-incubated for 30 mins before GM-CSF stimulati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed