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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM1773'
Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Pharmacyclics
US Patent
Ligand
BDBM1773
(US10280174, Comparative Compound 1 | US8476284, 4 ...)
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Affinity Data
Ki: 97nM
pH: 7.4
Assay Description:
Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology.
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