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Found 8 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM50087879'
LigandPNGBDBM50087879(CHEMBL472004 | NSC-87877)
Affinity DataIC50:  0.318nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50087879(CHEMBL472004 | NSC-87877)
Affinity DataIC50:  295nMAssay Description:Inhibition of Geranylgeranyl transferase type I from porcine brain tissueMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50087879(CHEMBL472004 | NSC-87877)
Affinity DataIC50:  318nMAssay Description:Inhibition of recombinant GST-fused human SHP2 (205 to 593 residues) using DiFMUP as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50087879(CHEMBL472004 | NSC-87877)
Affinity DataIC50:  318nMAssay Description:Inhibition of human recombinant GST-tagged SHP2 (205 to 593) expressed in Escherichia coli DH5-alpha using DiFMUP as substrate after 30 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50087879(CHEMBL472004 | NSC-87877)
Affinity DataIC50:  318nMAssay Description:Inhibition of human SHP2 (205 to 593 residues) using DiFMUP as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50087879(CHEMBL472004 | NSC-87877)
Affinity DataIC50:  318nMAssay Description:Inhibition of pig brain farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50087879(CHEMBL472004 | NSC-87877)
Affinity DataIC50:  320nMAssay Description:Inhibition of human SHP2 catalytic domain (205 to 593 residues) expressed in Escherichia coli DH5alpha using 6,8-difluoro-4-methylumbelliferyl phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50087879(CHEMBL472004 | NSC-87877)
Affinity DataIC50:  320nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed