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Found 3 Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50452200'
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50452200(CHEMBL4212416 | US10647727, Example 20)
Affinity DataKi:  5.5nMAssay Description:Binding affinity to PDE2 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50452200(CHEMBL4212416 | US10647727, Example 20)
Affinity DataKi:  6.10nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50452200(CHEMBL4212416 | US10647727, Example 20)
Affinity DataKi:  8.40nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent