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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50308553'
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50308553
((S)-3-(4-(2-hydroxypropyl)piperazin-1-yl)-1-(2-iso...)
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Affinity Data
IC50: 0.310nM
Assay Description:
Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assay
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Target Info
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