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Found 3 Enz. Inhib. hit(s) with Target = 'tRNA (cytosine(38)-C(5))-methyltransferase' and Ligand = 'BDBM50613350'
LigandPNGBDBM50613350(CHEMBL5285928)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of full-length human DNMT2 expressed in bacteria using tRNA-Asp as substrate and 3H-SAM as cosubstrate by tritium incorporation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50613350(CHEMBL5285928)
Affinity DataKd:  1.73E+4nMAssay Description:Binding affinity to full-length human DNMT2 expressed in bacteria assessed as apparent dissociation constant by ITC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50613350(CHEMBL5285928)
Affinity DataKd:  1.12E+4nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed