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Report error Found 2 Enz. Inhib. hit(s) with Target = 'von Hippel-Lindau disease tumor suppressor' and Ligand = 'BDBM536219'
Targetvon Hippel-Lindau disease tumor suppressor(Human)
Genentech

US Patent
LigandPNGBDBM536219((2S)-1-((2S,4R)-4-hydroxy-2-(5-methyl-5-(4-(4-meth...)
Affinity DataIC50:  7.79E+4nMAssay Description:The VHL NanoBRET™ Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL Nano...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

Targetvon Hippel-Lindau disease tumor suppressor(Human)
Genentech

US Patent
LigandPNGBDBM536219((2S)-1-((2S,4R)-4-hydroxy-2-(5-methyl-5-(4-(4-meth...)
Affinity DataIC50:  1.00E+5nMAssay Description:The VHL NanoBRET™ Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL Nano...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent