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Found 8 Enz. Inhib. hit(s) with all data for assayid = 18 entry = 50033857
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50344664(6,6-dimethyl-8-(1-(oxetan-3-yl)piperidin-4-yl)-11-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of ALK activity by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352764(CHEMBL1823220)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of ALK activity by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352760(CHEMBL1823221 | US9126931, 350)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of ALK activity by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352765(CHEMBL1823219)
Affinity DataIC50:  11nMAssay Description:Inhibition of ALK activity by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352763(CHEMBL1823222)
Affinity DataIC50:  15nMAssay Description:Inhibition of ALK activity by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50344663(6,6-dimethyl-8-(4-(oxetan-3-yl)piperazin-1-yl)-11-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of ALK activity by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352762(CHEMBL1823223)
Affinity DataIC50:  66nMAssay Description:Inhibition of ALK activity by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352761(CHEMBL1823361 | US9126931, 353)
Affinity DataIC50:  186nMAssay Description:Inhibition of ALK activity by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed