Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 6 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50000087
TargetCytochrome P450 1A2(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199201(6-Chloro-N-(pyridin-2-ylmethyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  240nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50014323(2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE | 2-Phenyl-benzo...)
Affinity DataIC50:  340nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranesMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel in guinea pig ventricular myocardium membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199190(6-Chloro-N-(3,4-dimethoxybenzyl)-1,2,3,4-tetrahydr...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in insect cells using EOMCC as substrate pretreated for 10 mins followed by substrate addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199197(6-Chloro-N-(3,4-dimethoxyphenethyl)-1,2,3,4-tetrah...)
Affinity DataIC50:  2.23E+4nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in insect cells using EOMCC as substrate pretreated for 10 mins followed by substrate addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM199186(N-(3,4-Dimethoxybenzyl)-1,2,3,4-tetrahydroacridin-...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in insect cells using EOMCC as substrate pretreated for 10 mins followed by substrate addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed