Affinity DataKi: 0.00300nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.00400nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.00400nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.00600nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.00700nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.00900nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.0190nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.0250nMAssay Description:Inhibition constant against human cathepsin L using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.0320nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.0360nMAssay Description:Inhibition constant against human cathepsin L using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.0720nMAssay Description:Inhibition constant against rat cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 0.0770nMAssay Description:Inhibition constant against human cathepsin B in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition constant against human cathepsin B in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Inhibition constant against human cathepsin H using L-Arg-b-naphthalamideMore data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:Inhibition constant against human cathepsin L using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity to insulin receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition constant against human cathepsin B in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition constant against human cathepsin H using L-Arg-b-naphthalamideMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity to IGF1R by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition constant against human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Binding affinity to insulin receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Binding affinity to IGF1R by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition constant against human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 830nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition constant against human cathepsin L using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Inhibition constant against human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 2.60E+3nMAssay Description:Inhibition constant against human cathepsin B in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 7.90E+3nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: >1.30E+4nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: >1.30E+4nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: >1.30E+4nMAssay Description:Inhibition constant against human cathepsin H using L-Arg-b-naphthalamideMore data for this Ligand-Target Pair
Affinity DataKi: >1.30E+4nMAssay Description:Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0480nMAssay Description:Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibiory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair