Affinity DataEC50: 1.10nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Inhibition of rat SGLT2More data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taiwan National Health Research Institutes
Curated by ChEMBL
Taiwan National Health Research Institutes
Curated by ChEMBL
Affinity DataEC50: 429nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taiwan National Health Research Institutes
Curated by ChEMBL
Taiwan National Health Research Institutes
Curated by ChEMBL
Affinity DataEC50: 593nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assayMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taiwan National Health Research Institutes
Curated by ChEMBL
Taiwan National Health Research Institutes
Curated by ChEMBL
Affinity DataEC50: 860nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taiwan National Health Research Institutes
Curated by ChEMBL
Taiwan National Health Research Institutes
Curated by ChEMBL
Affinity DataEC50: 1.39E+3nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Taiwan National Health Research Institutes
Curated by ChEMBL
Taiwan National Health Research Institutes
Curated by ChEMBL
Affinity DataEC50: 1.40E+3nMAssay Description:Inhibition of SGLT1 (unknown origin)More data for this Ligand-Target Pair