Found 38 of ec50 for monomerid = 23163 
Affinity DataEC50: 0.00500nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO cells assessed as cAMP accumulation after 30 mins by HTRF analysisMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 0.00560nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO cells assessed as ERK phosphorylation after 7 mins by alphaLISAMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0200nMAssay Description:Agonist activity at human recombinant S1P1 expressed in CHO cells assessed as stimulation of ERK phosphorylation incubated for 7 mins by microplate r...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0700nMAssay Description:Agonist activity at human recombinant C-terminal GFP-fused S1P1 expressed in CHO cells assessed as induction of receptor internalization incubated fo...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0700nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO cells co-expressing GFP assessed as cellular internalization after 45 mins by Hoechst assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0900nMAssay Description:Agonist activity at human S1P4 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataEC50: 0.100nMAssay Description:Activity at human S1P3 receptor expressed in HEK293T cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Activity at human S1P1 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.350nMAssay Description:Agonist activity at human S1P1 receptor expressed in human Chem1 cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.377nMAssay Description:Agonist activity at human S1P1 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Agonist activity at human S1P5 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.670nMAssay Description:Agonist activity at recombinant human S1P5 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Agonist activity at S1P1 receptor (unknown origin) expressed in PathHunter HEK 293 EDG1 Total GPCR Internalization cells assessed as receptor interna...More data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Agonist activity at recombinant human S1P1 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMpH: 7.4Assay Description:Agonism of human S1P-1 receptor expressed in CHO cells, 90-120 min in pH 7.4 using [35S]-GTP-gammaS as radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:Activity at human S1P1 receptor expressed in HEK293T cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:Effective concentration against sphingosine-1-phosphate receptor 1 determined by a [c-35S]-GTP binding assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataEC50: 1.40nMpH: 7.4Assay Description:Agonism of human S1P-3 receptor expressed in CHO cells, 90-120 min in pH 7.4 using [35S]-GTP-gammaS as radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at recombinant human S1P4 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.70nMAssay Description:Agonist activity at S1P1 receptor (unknown origin) expressed in PathHunter CHO-K1 EDG1 beta-arrestin cells assessed as induction of beta-arrestin 2 r...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Effective concentration against sphingosine 1-phosphate receptor 3 determined by a [c-35S]-GTP binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMpH: 7.4Assay Description:Agonism of human S1P-4 receptor expressed in CHO cells, 90-120 min in pH 7.4 using [35S]-GTP-gammaS as radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 3.40nMAssay Description:Agonist activity at S1P5 receptor (unknown origin) expressed in CHO cell membranes after 30 mins by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataEC50: 3.60nMAssay Description:Agonist activity at recombinant human S1P3 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataEC50: 3.60nMAssay Description:Agonist activity at human S1P3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Activity at human S1P5 receptor expressed in HEK293T cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Activity at human S1P4 receptor expressed in HEK293T cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.40nMAssay Description:Agonist activity at S1P1 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.90nMpH: 7.4Assay Description:Agonism of human S1P-5 receptor expressed in CHO cells, 90-120 min in pH 7.4 using [35S]-GTP-gammaS as radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 9.10nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO cells preincubated for 2 hrs before IP1 addition by IP1-HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at S1P5 receptor (unknown origin) expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation by GTPgammaS ...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataEC50: 14nMAssay Description:Agonist activity at S1PR3 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataEC50: 35nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells preincubated for 2 hrs before IP1 addition by IP1-HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Effective concentration against sphingosine 1-phosphate receptor 5 determined by a [c-35S]-GTP binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:Effective concentration against sphingosine 1-phosphate receptor 4 determined by a [c-35S]-GTP binding assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataEC50: 98nMAssay Description:Agonist activity at S1P3 receptor (unknown origin) expressed in PathHunter CHO-K1 EDG1 beta-arrestin cells assessed as induction of beta-arrestin 2 r...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMpH: 7.4Assay Description:Agonism of human S1P-2 receptor expressed in CHO cells, 90-120 min in pH 7.4 using [35S]-GTP-gammaS as radioligandMore data for this Ligand-Target Pair
