Found 5 of ec50 for monomerid = 50125935 TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataEC50: 1.20E+3nMAssay Description:Ability to enhance currents from alpha-1-beta-2-gamma-2L-subunit of GABA receptor elicited by low concentrations of GABAMore data for this Ligand-Target Pair
3D Structure (crystal)TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataEC50: 2.50E+3nMAssay Description:In vitro inhibition of 5-(125I)A-85380 binding to nicotinic acetylcholine receptor (nAChR) of rat brainMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 3.50E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataEC50: 1.10E+4nMAssay Description:Activity at human GABAA alpha1beta2gamma2s receptor expressed in HEK293 cells assessed as effect on GABA-induced current at 3 uM by whole cell patch-...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataEC50: 6.40E+4nMAssay Description:Enhancement of currents elicited by GABA at EC5 (6-12 uM)More data for this Ligand-Target Pair
