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Found 6 of ec50 for monomerid = 50509049
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509049(CHEMBL4440744)
Affinity DataEC50:  1.23E+3nMAssay Description:Agonist activity at STING in human wild-type THP1-Dual cells co-expressing ISRE reporter assessed as IRF-mediated immune response incubated for 24 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509049(CHEMBL4440744)
Affinity DataEC50:  3.10E+3nMAssay Description:Inhibition of wild type human STING by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509049(CHEMBL4440744)
Affinity DataEC50:  3.10E+3nMAssay Description:Induction of STING in human PBMC assessed as increase in IFNbeta secretionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509049(CHEMBL4440744)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at human wild type STINGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50509049(CHEMBL4440744)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity to C-terminal domain STING (139 to 379 residues) in human PBMC assessed as IFN-beta secretionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Zhejiang Normal University

Curated by ChEMBL
LigandPNGBDBM50509049(CHEMBL4440744)
Affinity DataEC50:  5.39E+4nMAssay Description:Induction of TBK1 in human PBMC assessed as increase in cGAMP secretionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed