TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University Of Baroda
Curated by ChEMBL
The M.S University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human COX-2 expressed in Baculovirus infected sf9 cells using arachidonic acid as substrate preincubated for 10 mins follow...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University Of Baroda
Curated by ChEMBL
The M.S University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against human recombinant cyclooxygenase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University Of Baroda
Curated by ChEMBL
The M.S University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:In Vitro activity of compound against human recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University Of Baroda
Curated by ChEMBL
The M.S University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Compound was tested for its inhibitory activity against recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University Of Baroda
Curated by ChEMBL
The M.S University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:In Vitro activity of compound against human recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University Of Baroda
Curated by ChEMBL
The M.S University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 5.01nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University Of Baroda
Curated by ChEMBL
The M.S University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
Affinity DataIC50: 43nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University Of Baroda
Curated by ChEMBL
The M.S University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 183nMAssay Description:Inhibition of human COX2 expressed in baculovirus-infected SF9 cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University Of Baroda
Curated by ChEMBL
The M.S University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 183nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibitory activity of compound against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University Of Baroda
Curated by ChEMBL
The M.S University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University Of Baroda
Curated by ChEMBL
The M.S University Of Baroda
Curated by ChEMBL
Affinity DataIC50: 660nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on thrombin-induced TXB2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant cyclooxygenase 2More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+4nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 1 in human whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.43E+4nMAssay Description:Inhibition of COX1 in LPS-induced human whole blood assessed as PGE2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+4nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataIC50: 9.62E+4nMAssay Description:Inhibition of ovine cyclooxygenase 1More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human cyclooxygenase-1 expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX1 expressed in african green monkey COS cells assessed as inhibition of arachidonic acid-stimulated PGE2 treated 1 hr before a...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+5nMAssay Description:Compound was tested for its inhibitory activity against recombinant human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+5nMAssay Description:In Vitro activity of compound against human recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.57E+5nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair