BindingDB PrimarySearch

Found 2 of ic50 for monomerid = 15378

Heat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Ribotargets

Curated by ChEMBL

BDBM15378(9-butyl-8-(2,5-dimethoxybenzyl)-9H-purin-6-amine |...)

IC50: 4.10E+4nMAssay Description:Inhibition of ATP-ase activity in human colon tumour cell line (HCT116)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL DrugBank MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

ATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
Vernalis (R&D)

BDBM15378(9-butyl-8-(2,5-dimethoxybenzyl)-9H-purin-6-amine |...)

IC50: 4.10E+4nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL DrugBank MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed