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Found 4 of ic50 for monomerid = 171819
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM171819(US9085576, 320)
Affinity DataIC50:  15nMAssay Description:Inhibition of BACE1 in HEK293 cellsMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM171819(US9085576, 320)
Affinity DataIC50:  56.5nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM171819(US9085576, 320)
Affinity DataIC50:  81nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM171819(US9085576, 320)
Affinity DataIC50: >4.00E+5nMpH: 3.5Assay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
In DepthDetails US Patent