Compile Data Set for Download or QSAR
Report error Found 4 of ic50 for monomerid = 30972
TargetAldehyde dehydrogenase 1A1(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM30972(8-[[4-(furan-2-carbonyl)piperazin-1-yl]methyl]-1,3...)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant human ALDH1A1 using propionaldehyde as substrate preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldehyde dehydrogenase 1A1(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM30972(8-[[4-(furan-2-carbonyl)piperazin-1-yl]methyl]-1,3...)
Affinity DataIC50: 800nMAssay Description:Inhibition of ALDH1A1 (unknown origin) assessed as inhibition of propionaldehyde oxidationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldehyde dehydrogenase 1A1(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM30972(8-[[4-(furan-2-carbonyl)piperazin-1-yl]methyl]-1,3...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human ALDH1A1 using propionaldehyde as substrate in presence of NAD+ by UV-visible spectrophometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAldehyde dehydrogenase 1A1(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM30972(8-[[4-(furan-2-carbonyl)piperazin-1-yl]methyl]-1,3...)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of N-terminal Met/His6-tagged recombinant human ALDH1A1 (Ser2-Ser501 residues) expressed in Escherichia coli cells using propionaldehyde a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)