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Found 3 of ic50 for monomerid = 444446
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444446(US10662159, Example 31)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444446(US10662159, Example 31)
Affinity DataIC50: >1.00E+3nMAssay Description:Rat/homo FAAH:Procedure was followed as described for hMGL, except that arachidonoyl-methyl coumarin (was used as fluorigenic substrate. Compounds we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444446(US10662159, Example 31)
Affinity DataIC50: >1.00E+3nMAssay Description:MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent