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Found 16 of ic50 for monomerid = 50003399
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  170nMAssay Description:Ability to displace [125I]-labeled angiotensin II from its receptor of a rat uterus membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at angiotensin 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  230nMAssay Description:Displacement of [125I]-Sar1-Ile8-A II at the rabbit aorta angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  230nMAssay Description:Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  300nMAssay Description:Binding affinity against angiotensin II receptor type 1 (AT1) from rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  330nMAssay Description:Ability to displace [125I]-labeled angiotensin II from its receptor of a rat uterus membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  330nMAssay Description:Ability to displace [125I]-labeled angiotensin II from its receptor of a rat uterus membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  350nMAssay Description:Inhibition of specific binding of [125I]-angiotensin-II to angiotensin 1 receptor in rat lung membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Cavia porcellus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  430nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  480nMAssay Description:Concentration required for 50% displacement of the specifically bound [3-[125I]-iodotyrosyl]-angiotensin II from angiotensin II receptor in the membr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  490nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  490nMAssay Description:Inhibition of [125l]-All binding to bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(RAT)
Searle

Curated by ChEMBL
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  3.30E+3nMAssay Description:Activity against low affinity Angiotensin II receptor, type 2 was measured from the ability to inhibit [125I]-angiotensin II binding to rat uterine m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory concentration that gives 50% displacement of specific binding at labeled angiotensin II type 1 receptor in rat adrenal cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A/B(RAT)
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory concentration that gives 50% displacement of specific binding at labeled angiotensin II type 1 receptor in rat adrenal cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50003399(4'-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-yl...)
Affinity DataIC50:  1.70E+5nMAssay Description:Activity against high affinity Angiotensin II receptor, type 1 was measured from the ability to inhibit [125I]-angiotensin II binding to rat uterine ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed