Found 62 of ic50 for monomerid = 50235833 
Affinity DataIC50: 23nMAssay Description:Inhibition of C-terminal His-tagged Syk catalytic domain (356 to 635 residues) (unknown origin) using biotin-TYR1 as substrate after 60 mins by TR-FR...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 24nMAssay Description:Inhibition of Syk (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of TNK2 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of TTK (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 2.75E+3nMAssay Description:Inhibition of JNK1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of RET (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 4.14E+3nMAssay Description:Inhibition of TYRO3 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 16(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
Affinity DataIC50: 4.79E+3nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 4.98E+3nMAssay Description:Inhibition of ZIPK (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.22E+3nMAssay Description:Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.94E+3nMAssay Description:Inhibition of ALK (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.96E+3nMAssay Description:Inhibition of Fyn (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetLeukocyte tyrosine kinase receptor(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 6.01E+3nMAssay Description:Inhibition of LTK (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 6.24E+3nMAssay Description:Inhibition of MAP4K2 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 6.79E+3nMAssay Description:Inhibition of PAK4 kinase domain (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.51E+3nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of CK1alpha1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 8.54E+3nMAssay Description:Inhibition of KDR (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 9.43E+3nMAssay Description:Inhibition of MAP4K4 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 9.96E+3nMAssay Description:Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated plateletsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Potency was measured by the displacement of [3H]-spiperone binding to human D4 dopaminergic receptorMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CSF1R (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ROCK2 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TRKA (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK2 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDGFRB (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BTK (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of INSR (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of DYRK1B (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ROCK1(unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MEK2 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GSK3B (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AURKA (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ACVR1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK8 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK9 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Wee1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AURKB (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TAO2(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TAOK2 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CAMK1D (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PKCtheta (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GSK3A (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CLK2 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase D3(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Prkcn (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor-like protein(Homo sapiens (Human))
Abbvie Bioresearch Center
Curated by ChEMBL
Abbvie Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MST1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
