Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ic50 for monomerid = 50340805
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340805(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340805(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)
Affinity DataIC50:  150nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50340805(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Merck

Curated by ChEMBL
LigandPNGBDBM50340805(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed