Compile Data Set for Download or QSAR
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Found 4 of ic50 for monomerid = 50425824
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50425824(CHEMBL2312289)
Affinity DataIC50:  98nMAssay Description:Inhibition of full length SIRT1 (unknown origin) by fluorometric enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50425824(CHEMBL2312289)
Affinity DataIC50:  990nMAssay Description:Inhibition of N-terminal hexa-His-tagged human SIRT1 (156 to 664 residues) expressed in Escherichia coli BL21 (DE3) assessed as deacetylation of Abz-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50425824(CHEMBL2312289)
Affinity DataIC50:  8.69E+3nMAssay Description:Inhibition of GST-fusion tagged human SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 (DE3) using Abz-GVLKacAYNO2GY-NH2 peptide as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50425824(CHEMBL2312289)
Affinity DataIC50:  2.92E+4nMAssay Description:Inhibition of N-terminal TEV cleavage site-fused hexa-His-tagged human SIRT3 (118 to 399 residues) expressed in Escherichia coli BL21 (DE3) using Abz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed