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Found 12 of ic50 for monomerid = 50527134
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50:  0.00800nMAssay Description:Inhibition of CD73 in human CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2....More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50:  0.0110nMAssay Description:Inhibition of CD73 in human PBMC using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2.5 hrs by PiColor...More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50:  0.0410nMAssay Description:Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 ...More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50:  0.0430nMAssay Description:Inhibition of soluble human CD73More data for this Ligand-Target Pair
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50:  0.660nMAssay Description:Inhibition of CD73 in mouse CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2....More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50:  0.860nMAssay Description:Inhibition of human C-terminal His6-tagged CD73 expressed in CHO cells preincubated for 15 mins followed by AMP addition and measured after 10 mins b...More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50:  2.02nMAssay Description:Test compound solution preparation: Stock solution of a test compound was prepared in DMSO at 10 mM concentration. A series of preset 10-concentratio...More data for this Ligand-Target Pair
TargetEctonucleoside triphosphate diphosphohydrolase 8(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50: >10nMAssay Description:Inhibition of NTPDase 8 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 3(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50: >10nMAssay Description:Inhibition of NTPDase 3 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50: >10nMAssay Description:Inhibition of NTPDase 2 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50: >10nMAssay Description:Inhibition of CD39 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed