Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of ic50 for monomerid = 50536216
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50536216(CHEMBL4580425)
Affinity DataIC50:  4nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50536216(CHEMBL4580425)
Affinity DataIC50:  14nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50536216(CHEMBL4580425)
Affinity DataIC50:  20nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50536216(CHEMBL4580425)
Affinity DataIC50:  398nMAssay Description:Inhibition of JAK in human B lymphocyte cells assessed as suppression of IL4-induced STAT6 phosphorylation preincubated for 1 hr followed by IL4 addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL
LigandPNGBDBM50536216(CHEMBL4580425)
Affinity DataIC50:  794nMAssay Description:Inhibition of human Gst-tagged TYK2 ( 871 to 1187 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed