Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ic50 for monomerid = 50545945
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50545945(CHEMBL4777342)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human GST-tagged TAF1 BD2 (1519 to 1651 residues) expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 preincubated for 15 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50545945(CHEMBL4777342)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of JAK in human BEAS-2B cells assessed as reduction in IL13-induced STAT6 phosphorylation incubated for 1 hr followed by IL13 addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50545945(CHEMBL4777342)
Affinity DataIC50:  81nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus expression system using LRRKtide as substrate incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed