Affinity DataIC50: 10nMAssay Description:Inhibition of bovine MAO-A by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Central Food Technological Research Institute
Curated by ChEMBL
Central Food Technological Research Institute
Curated by ChEMBL
Affinity DataIC50: 14.8nMAssay Description:Inhibition of cataracted human eye lens aldose reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against PIM1More data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of human CYP1B1 by EROD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of CYP1B1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 174nMAssay Description:Inhibition of MMP9 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Tokushima Bunri University
Curated by ChEMBL
Tokushima Bunri University
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Tokushima Bunri University
Curated by ChEMBL
Tokushima Bunri University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory activity against RBL-1 5-LOMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Tokushima Bunri University
Curated by ChEMBL
Tokushima Bunri University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cellsMore data for this Ligand-Target Pair
TargetM18 aspartyl aminopeptidase(Plasmodium falciparum 3D7)
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 385nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Tokushima Bunri University
Curated by ChEMBL
Tokushima Bunri University
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Iin vitro inhibition of 5-lipoxygenase activity in rat basophil leukemia type 1(RBL1) cell homogenates, (reduction of [14C]-5-HETE formation)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
Tahitian Noni International
Curated by ChEMBL
Tahitian Noni International
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of 15LOX in rabbit reticulocytes by EIA assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile
Curated by ChEMBL
Universidad De Santiago De Chile
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Tokushima Bunri University
Curated by ChEMBL
Tokushima Bunri University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of 5-lipoxygenase in rat (peritoneal assay)More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of human recombinant CK2 expressed in Escherichia coli using RRRADDSDDDDD as substrate after 10 mins in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of wild type MET (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Dongguk University-Seoul
Curated by ChEMBL
Dongguk University-Seoul
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant FLT3 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of His6-tagged HIV-1 integrase assessed as decrease in integrase-Flag-LEDGF/p75 interaction preincubated with enzyme for 30 mins followed ...More data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assayMore data for this Ligand-Target Pair
TargetInositol hexakisphosphate kinase 2(Homo sapiens)
National Institute Of Environmental Health Sciences
Curated by ChEMBL
National Institute Of Environmental Health Sciences
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of human IP6K2 using insP6 as substrate preincubated for 15 mins followed by substrate and measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Tahitian Noni International
Curated by ChEMBL
Tahitian Noni International
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of 5LOX in human PBMC by EIA assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CYP1B1 expressed in yeast microsomal membranes using 7-ethoxyresorufin as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against L-Hexonate Dehydrogenase from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of PIM1 kinaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Competitive inhibition of PIM1 in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMpH: 7.0 T: 2°CAssay Description:The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human CYP1A1 by EROD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of CYP1A1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Heinrich-Heine-Universit£T D£Sseldorf
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of LSD1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of myeloperoxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of MPO in human neutrophils using H2O2 as substrate measured after 1 hr by fluorescence based HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate after 8 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of ELAV1 (unknown origin)-ARE TNFalpha complex formation after 20 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetInterstitial collagenase [100-268](Homo sapiens (Human))
East China University of Science and Technology
East China University of Science and Technology
Affinity DataIC50: 1.49E+3nMpH: 7.5Assay Description:The activity of cd-MMP-1 was measured using a fluorescence-based assay. It was performed in white 96-well half area microplate (Greiner) in a final v...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
University Of Zurich
Curated by ChEMBL
University Of Zurich
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of FabIMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human thrombin amidolytic activity using D-Phe-Pip-Arg-pNA as substrate preincubated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
University Of Zurich
Curated by ChEMBL
University Of Zurich
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Plasmodium falciparum FabIMore data for this Ligand-Target Pair