Affinity DataIC50: 135nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using 11-deoxycorticosterone substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate after 30 mins by fluorescence-based colorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 456nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using 11-deoxycorticosterone substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 709nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland
Curated by ChEMBL
University Of The West Of Scotland
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland
Curated by ChEMBL
University Of The West Of Scotland
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human CYP4Z1 overexpressed in human MCF7 cells using luciferin-BE as substrate incubated for 24 hrs followed by substrate addition by l...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human CYP4Z1 overexpressed in human MCF7 cells using luciferin-3FBE as substrate incubated for 24 hrs followed by substrate addition by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of wild type cytochrome P450cam expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland
Curated by ChEMBL
University Of The West Of Scotland
Curated by ChEMBL
Affinity DataIC50: 3.91E+4nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland
Curated by ChEMBL
University Of The West Of Scotland
Curated by ChEMBL
Affinity DataIC50: 5.09E+4nMAssay Description:Inhibition of rat testis 17,20 lyase component of P450-17alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 7.75E+4nMpH: 7.4Assay Description:All procedures were carried out under minimal light in order to prevent degradation of the retinoid samples.Microsomal preparation: one lobe of fresh...More data for this Ligand-Target Pair
Affinity DataIC50: 7.75E+4nMpH: 7.4 T: 2°CAssay Description:Microsomal preparation: One lobe of fresh pig liver is obtained (e.g., at about the time of slaughter from a food-processing company) and immediately...More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland
Curated by ChEMBL
University Of The West Of Scotland
Curated by ChEMBL
Affinity DataIC50: 1.54E+5nMAssay Description:Inhibition of rat testis 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The West Of Scotland
Curated by ChEMBL
University Of The West Of Scotland
Curated by ChEMBL
Affinity DataIC50: 2.15E+5nMAssay Description:Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair