Compile Data Set for Download or QSAR
maximum 50k data
Found 8 of ki for monomerid = 50038879
TargetProlyl endopeptidase(Bos taurus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50038879((S)-2-(2-Formyl-pyrrolidine-1-carbonyl)-pyrrolidin...)
Affinity DataKi:  0.210nMAssay Description:Inhibition of bovine brain POPMore data for this Ligand-Target Pair
TargetProlyl endopeptidase(Bos taurus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50038879((S)-2-(2-Formyl-pyrrolidine-1-carbonyl)-pyrrolidin...)
Affinity DataKi:  0.350nMAssay Description:Inhibition of POP in bovine serum using Z-Gly-Pro-NH-Mec fluorimetric substrateMore data for this Ligand-Target Pair
TargetProlyl endopeptidase(Mus musculus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50038879((S)-2-(2-Formyl-pyrrolidine-1-carbonyl)-pyrrolidin...)
Affinity DataKi:  0.350nMAssay Description:Inhibition of mouse brain POPMore data for this Ligand-Target Pair
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50038879((S)-2-(2-Formyl-pyrrolidine-1-carbonyl)-pyrrolidin...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of recombinant human POP assessed as affinity constant of second step of inhibition pre-incubated for 2 hrs before addition of ZGP-pNA sub...More data for this Ligand-Target Pair
TargetProlyl endopeptidase(Flavobacterium meningosepticum)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50038879((S)-2-(2-Formyl-pyrrolidine-1-carbonyl)-pyrrolidin...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of Flavobacterium meningosepticum POPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50038879((S)-2-(2-Formyl-pyrrolidine-1-carbonyl)-pyrrolidin...)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50038879((S)-2-(2-Formyl-pyrrolidine-1-carbonyl)-pyrrolidin...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of prolyl oligopeptidaseMore data for this Ligand-Target Pair
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50038879((S)-2-(2-Formyl-pyrrolidine-1-carbonyl)-pyrrolidin...)
Affinity DataKi:  8nMAssay Description:Inhibition of recombinant human POP assessed as affinity constant of first step of the binding event pre-incubated for 2 hrs before addition of ZGP-p...More data for this Ligand-Target Pair