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Targets 22▿
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 286
Peroxisome proliferator-activated receptor delta 144
Hematopoietic prostaglandin D synthase 127
Peroxisome proliferator-activated receptor gamma 126
Nitric oxide synthase, brain 106
Nitric oxide synthase, endothelial 103
Nitric oxide synthase, inducible 101
Peroxisome proliferator-activated receptor alpha 90
Beta-1 adrenergic receptor 32
Beta-2 adrenergic receptor 32
Beta-3 adrenergic receptor 31
Protein kinase C alpha/beta/gamma type 22
Cytochrome P450 3A4 15
Estrogen-related receptor gamma 12
Potassium voltage-gated channel subfamily H member 2 7
Cytochrome P450 1A2 3
Cytochrome P450 2C9 3
Cytochrome P450 2C19 3
Protein kinase C alpha type 3
Cytochrome P450 2D6 3
cAMP-dependent protein kinase catalytic subunit alpha 2
Prostaglandin-H2 D-isomerase 1
...
Publications 16▿
Bioorg Med Chem Lett 21: 2345 -50 (2011) 178 J Med Chem 58: 3548 -71 (2015) 172 J Med Chem 41: 2858 -71 (1998) 150 Bioorg Med Chem Lett 18: 5018 -22 (2008) 105 J Med Chem 40: 1901 -5 (1997) 88 J Med Chem 58: 7021 -56 (2015) 83 J Med Chem 53: 1857 -61 (2010) 51 Bioorg Med Chem Lett 10: 597 -600 (2000) 48 Bioorg Med Chem Lett 17: 4670 -7 (2007) 48 Bioorg Med Chem 26: 2107 -2150 (2018) 47 J Med Chem 49: 2758 -71 (2006) 47 Bioorg Med Chem Lett 17: 3916 -20 (2007) 36 J Med Chem 34: 2928 -31 (1991) 27 Bioorg Med Chem Lett 7: 1763 -1768 (1997) 24 J Med Chem 48: 3107 -9 (2005) 12 Bioorg Med Chem Lett 21: 5568 -72 (2011) 6 Institutions 6▿
Glaxosmithkline 621 Glaxo Wellcome Research And Development 286 Gsk 117 Glaxosmithkline Research and Development 47 Nova Pharmaceutical 27 TBA 24 Affinity: 0.063 to 1.0E+6 nM▿
Xtal structures: 16
Docked structures: 1
Catalog Cmpds: 26
Found 1 with your filter 
3D Structure (crystal)