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Replicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute For Translational Medicine and Pharmacology (Itmp) and Fraunhofer Cluster of Excellence For Immune Mediated Diseases (Cimd

BDBM50069985((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...)

EC50: 120nMAssay Description:anti-cytopathic effect in a Vero-E6 cell line.More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Details Article

Filter my 72 hits

Targets 5▿
- Replicase polyprotein 1ab 43
- Protein kinase C delta type 22
- Phosphatidylinositol 4-kinase beta 3
- RNA-directed RNA polymerase 3
- Phosphatidylinositol 4-kinase type 2-alpha 1
Publications 5▿
- bioRxiv 2020: (2020) 43
- J Nat Prod 79: 680-4 (2016) 22
- J Med Chem 57: 3247-62 (2014) 3
- ACS Med Chem Lett 4: 585-9 (2013) 3
- Bioorg Med Chem 23: 184-91 (2014) 1
Institutions 5▿
- Fraunhofer Institute For Translational Medicine and Pharmacology (Itmp) and Fraunhofer Cluster of Excellence For Immune Mediated Diseases (Cimd 43
- Stanford University 22
- Biofocus 3
- Universit£ 3
- Academy Of Sciences Of The Czech Republic 1
Affinity: 1.1 to 1.3E+5 nM▿
- Ki 22
- IC50 49
- EC50 1
- Affinity ≤ nM
Xtal structures: 3
Docked structures: 0
Catalog Cmpds: 28