Found 74 of ic50 for monomerid = 10755 
Affinity DataIC50: 0nMAssay Description:Agonist required to inhibit Dopamine receptor D2 photoinactivation by 50% with Iodazidoclebopride using [3H]-SpiperoneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataIC50: 0.470nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:In vitro inhibition of [125I]DOI binding to 5-hydroxytryptamine 2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.940nMAssay Description:Inhibition of [125I]DOI binding to 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:In vitro inhibitory concentration required against [3H]8-OH-DPAT binding to cloned human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at recombinant human 5-HT2C expressed in human U2OS cells by pathhunter beta-arrestin assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Compound was tested in vitro for the inhibition of azido-[125I]-IPAPP (0.25 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Compound was tested in vitro for the inhibition of [3H]-DPAT (1 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataIC50: 2.55nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of radiolabeled [3H]-8-OH-DPAT ligand binding to 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Binding affinity of the compound was measured against serotonin 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-hydroxytryptamine 1A receptor of guinea pig hippocampus.More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Tested in vitro for receptor binding affinity to 5-hydroxytryptamine 1D receptor in bovine caudate using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity was determined by the relaxation of the carbachol-contracted rat esophageal tunica muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of radiolabeled [3H]-5-HT ligand binding to 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]CYP from rat cerebral cortex 5-HT1B receptor in the presence of isoproternolMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]CYP from rat cerebral cortex 5HT1B receptor measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT in mouse hippocampusMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Binding affinity of the compound against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Tested in vitro for receptor binding affinity to 5-hydroxytryptamine 1A receptor in rat cortex using [3H]-OH-DPAT radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Binding affinity of the compound against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Binding affinity of the compound was measured against serotonin 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Compound was tested in vitro for the inhibition of [125I]-IPAPP (0.25 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Compound was tested in vitro for the inhibition of [3H]-5-HT (2 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Sus scrofa)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Binding activity against 5-hydroxytryptamine 1D receptor from pig caudate membrane using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Sus scrofa)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Sus scrofa)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Compound was tested for the displacement of [3H]-5-HT to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity of the compound against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 27.5nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at recombinant human 5-HT2A expressed in human U2OS cells by pathhunter beta-arrestin assayMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of radiolabeled [3H]mesulergine ligand binding to 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Binding affinity of the compound against 5-hydroxytryptamine 1C receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]-mesulergine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in CHO cells measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT6 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 147nMAssay Description:Inhibition of radiolabeled [3H]GR-113808 ligand binding to 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT5A receptor expressed in HEK293 cells measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT5A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT5a receptor in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 323nMAssay Description:Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assayMore data for this Ligand-Target Pair
