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Found 4 of ic50 for monomerid = 12657
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM12657(1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsul...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
TargetComplement factor H(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM12657(1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsul...)
Affinity DataIC50:  4.40E+4nMAssay Description:In vitro activity against human Complement factor IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM12657(1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsul...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Trypsin using S-2238 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM12657(1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsul...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Thrombin using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed