Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ec50 for monomerid = 202784
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM202784(US10245267, Example 131 | US10709712, Example 131 ...)
Affinity DataEC50:  20nMAssay Description:Inhibition CRAF in human Calu6 cells assessed as decrease in MEK phosphorylation after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM202784(US10245267, Example 131 | US10709712, Example 131 ...)
Affinity DataEC50:  6nMAssay Description:Inhibition of CRAF in human Calu6 cells assessed as reduction MEK phosphorylation measured after 1 hr by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase/Serine/threonine-protein kinase B-raf(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM202784(US10245267, Example 131 | US10709712, Example 131 ...)
Affinity DataEC50:  796nMAssay Description:Stimulation of BRAF-CRAF dimerization in human HCT116 cells by luciferase complementation assayMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM202784(US10245267, Example 131 | US10709712, Example 131 ...)
Affinity DataEC50:  100nMAssay Description:Inhibition of CRAF in human Calu6 cells assessed as decrease in ERK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed