TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of human AKR1C3 expressed in Escherichia coli BL21(DE3) pLysS cells using 9,10-phenanthrenequinone as substrateMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of human AKR1C3 expressed in Escherichia coli BL21(DE3) pLysS cells using S-tetralol as substrateMore data for this Ligand-Target Pair
TargetFatty acid-binding protein, heart(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of 8-anilino-1-naphthalene-sulfonic acid from human His-FABP3 expressed in Escherichia coli BL21 (DE3) cells after 3 mins relative to li...More data for this Ligand-Target Pair
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of 8-anilino-1-naphthalene-sulfonic acid from human His-FABP4 expressed in Escherichia coli BL21 (DE3) cells after 3 mins relative to li...More data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Allosteric inhibition of soybean LO1More data for this Ligand-Target Pair
TargetFatty acid-binding protein, heart(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FABP3 (unknown origin) relative to linoleic acidMore data for this Ligand-Target Pair
TargetFatty acid-binding protein, heart(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FABP4 (unknown origin) relative to linoleic acidMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of PPAR-alpha (unknown origin) by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20E+3nMAssay Description:Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assayMore data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Competitive inhibition of soybean LO1More data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Mixed-type inhibition of soybean LO1More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.36E+4nMAssay Description:Displacement of 8-anilino-1-naphthalene-sulfonic acid from human His-FABP4 expressed in Escherichia coli BL21 (DE3) cells after 3 minsMore data for this Ligand-Target Pair
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of FABP4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of amidolytic activity of human tissue factor/human factor 7aMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of aromatase in human placental microsomes by radiometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+4nMAssay Description:Displacement of [3H]DPCPX from rat adenosine A1 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Xiamen University
Curated by ChEMBL
Xiamen University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GST-tagged human HePTP using pNpp as substrate after 30 minsMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Xiamen University
Curated by ChEMBL
Xiamen University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GST-tagged human VHR using pNpp as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of pig pancreatic trypsin after 15 minsMore data for this Ligand-Target Pair
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against human Acyl coenzyme A:cholesterol acyltransferase 2More data for this Ligand-Target Pair
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against rat liver microsomal Acyl coenzyme A:cholesterol acyltransferaseMore data for this Ligand-Target Pair
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against human Acyl coenzyme A:cholesterol acyltransferase 1More data for this Ligand-Target Pair