Found 34 of ic50 for monomerid = 34651 TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory activity against Phosphodiesterase 3 from heart.More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from human platelets at 1E-7-1E-4M or 1.0E-6 to 1E-3 MMore data for this Ligand-Target Pair
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of human recombinant PDE3 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:In vitro inhibitory activity against cAMP phosphodiesterase III in dog aortaMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of low Km cyclic cAMP phosphodiesterase PDE III of guinea pig ventricleMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of canine heart Phosphodiesterase 4More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of cAMP PDE II enzymeMore data for this Ligand-Target Pair
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of fraction III of guinea pig phosphodiesteraseMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration against cAMP PDE III enzyme in guinea pigMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 1.875 mg/kg intravenous doseMore data for this Ligand-Target Pair
TargetPerilipin-5(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 7.88E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetPerilipin-1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: >7.95E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibitory activity against Phosphodiesterase 4 from heart.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of canine heart phosphodiesterase 4More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of canine kidney Phosphodiesterase 4 at 0.5 uMMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: 1.50E+5nMAssay Description:Cardiotonic effect by inhibition of cAMP phosphodiesterase (PDE III)More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibitory activity against PDE1 from cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 3.71E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 5.80E+5nMAssay Description:Inhibition of cGMP PDE II enzymeMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 5.80E+5nMAssay Description:Inhibition of cGMP PDE II enzymeMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibition of cyclic GMP sensitive phosphodiesterase PDE 2 of guinea pig ventricleMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 7.20E+5nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 7.20E+5nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition cGMP PDE I enzymeMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of cAMP PDE I enzymeMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration against cGMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration against cGMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of guinea pig ventricleMore data for this Ligand-Target Pair
